Cobra

Liquid Free Sample Cooling For XRD in Cryostallography and Spectroscopy

The Cobra is a cryogen free open-flow cooler with precise temperature controls in the range of 80-500K. Instead of using liquid nitrogen to sustain those temperatures it uses helium in a closed cycle to cool a stream of nitrogen gas, meaning your laboratory can be completely free from the pains of LN2 storage, dewar management and safety procedures. Plus, with a continuous supply of nitrogen, the Cobra can perform without interruption or intervention, perfect for high-throughput screenings in drug discovery or materials science.

Benefits

  • Temperature Range:  80-400 K or 80-500 K (Standard or Plus)
  • Cryogen:  None (Mechanically Cooled)
  • Stability:  +/- 0.1 K
  • Fast Cool Down:  ~60 minutes (~50 minutes to 100K)
  • Run-Time:  Endless

Typical Applications

  • High-throughput screenings in drug discovery or materials science
  • High-precision solution and refinement of crystal structures
  • Protein crystallography
  • Investigation of phase transitions
  • Stability and morphology of drug crystals

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Refrigerator & Gas Head*
Dimensions & Weight28 x 20 x 28 mm, 15 kg
N2 Intake5 or 10 l/min
K450 Helium Compressor
Weights & Dimensions64 x 61 x 54 cm, 100 kg
Supply Fuse Rating20 A (Starting Current: 65 A)
Cooling Requirements3kW Water Chiller or plumbed supply
Flow rate 5l/min at 18°C
N2 Supply (Required)
Purity>97.5%
Pressure1 – 1.4 bar
Flow~25 l/minute

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* These items are permanently joined and form an integrated assembly

Water Chiller not provided

Regulator Kit available

Accessories

The base Cobra system contains the main refrigeration unit with attached a gas delivery head, and a helium compressor. Alongside this base system, users have the option to enhance their setup with additional accessories.

NitroFlow Nitrogen Gas Generator

For laboratories that do not have an in-house supply of nitrogen, we supply a bespoke variant on the Parker Hannifin NitroFlow Nitrogen Gas Generator, which extracts pure nitrogen from the air. The generator has 2 outlet ports, providing gas at 1.2 bar for both inner and outer gas streams of the Cobra.

Cobra Table Stand

This table stand has been specifically designed to house the various components of the Cobra system, providing an organised space to manage cables and wires.

Varibeam

The Varibeam stand provides a sturdy yet lightweight support for the coldhead, designed for compatible with a range diffractometer configurations. It facilitates easy and precise adjustment of orientation and positioning of the nozzle to ensures accurate alignment of the gas stream onto the sample.

Customisation

These options are tailored to meet the specific requirements of our customers. If you have a customisation in mind for your Cobra that is not covered in the options listed, we’d love to know.

Plus

Increase the upper temperature range to 500 K

Compact

A variation on the Plus which features a shortened nozzle. This design allows compatibility with powder diffractometers, facilitating high-resolution studies of both organic and inorganic compounds.

Wide Nozzle

A 146% increase to the sample area. Accomodates analysis of large samples, or allows the nozzle to be moved further away to minimise x-ray shadowing